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Mitochondrial fusion occurs through the mediation of.by MFN1, MFN2, and optic atrophy protein 1 (OPA1), and mitochondrial fission is mediated by Drp1, mitochondrial fission protein 1 (FIS1), and MFF [87, 88]

Thus, there is hope that this particular vascular recovering effect of the BPC 157 therapy [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41] could finally bring into practice the huge theoretical importance of cytoprotective agents (i.e., selectivity for the damaged epithelium and/or selectivity for the damaged endothelium [10,11,12]) long ago proposed in the series of cytoprotection funding reports [10,11,12,13,14,15,16,17]